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Constructing the Energy Landscape for Genetic Switching System Driven by Intrinsic Noise

Genetic switching driven by noise is a fundamental cellular process in genetic regulatory networks. Quantitatively characterizing this switching and its fluctuation properties is a key problem in computational biology. With an autoregulatory dimer model as a specific example, we design a general met...

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Detalles Bibliográficos
Autores principales: Lv, Cheng, Li, Xiaoguang, Li, Fangting, Li, Tiejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923795/
https://www.ncbi.nlm.nih.gov/pubmed/24551081
http://dx.doi.org/10.1371/journal.pone.0088167