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Constructing the Energy Landscape for Genetic Switching System Driven by Intrinsic Noise
Genetic switching driven by noise is a fundamental cellular process in genetic regulatory networks. Quantitatively characterizing this switching and its fluctuation properties is a key problem in computational biology. With an autoregulatory dimer model as a specific example, we design a general met...
Autores principales: | Lv, Cheng, Li, Xiaoguang, Li, Fangting, Li, Tiejun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923795/ https://www.ncbi.nlm.nih.gov/pubmed/24551081 http://dx.doi.org/10.1371/journal.pone.0088167 |
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