Conformational Changes in Acetylcholine Binding Protein Investigated by Temperature Accelerated Molecular Dynamics

Despite the large number of studies available on nicotinic acetylcholine receptors, a complete account of the mechanistic aspects of their gating transition in response to ligand binding still remains elusive. As a first step toward dissecting the transition mechanism by accelerated sampling techniq...

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Detalles Bibliográficos
Autores principales: Mohammad Hosseini Naveh, Zeynab, Malliavin, Therese E., Maragliano, Luca, Cottone, Grazia, Ciccotti, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923797/
https://www.ncbi.nlm.nih.gov/pubmed/24551117
http://dx.doi.org/10.1371/journal.pone.0088555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923797/
https://www.ncbi.nlm.nih.gov/pubmed/24551117
http://dx.doi.org/10.1371/journal.pone.0088555

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