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Conformational Changes in Acetylcholine Binding Protein Investigated by Temperature Accelerated Molecular Dynamics
Despite the large number of studies available on nicotinic acetylcholine receptors, a complete account of the mechanistic aspects of their gating transition in response to ligand binding still remains elusive. As a first step toward dissecting the transition mechanism by accelerated sampling techniq...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923797/ https://www.ncbi.nlm.nih.gov/pubmed/24551117 http://dx.doi.org/10.1371/journal.pone.0088555 |