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MicroRNA-Target Binding Structures Mimic MicroRNA Duplex Structures in Humans

Traditionally, researchers match a microRNA guide strand to mRNA sequences using sequence comparisons to predict its potential target genes. However, many of the predictions can be false positives due to limitations in sequence comparison alone. In this work, we consider the association of two relat...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Shen, Lu, Chou, Hui-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923817/
https://www.ncbi.nlm.nih.gov/pubmed/24551166
http://dx.doi.org/10.1371/journal.pone.0088806