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Fibroblast Activation Protein (FAP) Is Essential for the Migration of Bone Marrow Mesenchymal Stem Cells through RhoA Activation

BACKGROUND: The ability of human bone marrow mesenchymal stem cells (BM-MSCs) to migrate and localize specifically to injured tissues is central in developing therapeutic strategies for tissue repair and regeneration. Fibroblast activation protein (FAP) is a cell surface serine protease expressed at...

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Detalles Bibliográficos
Autores principales: Chung, Kuei-Min, Hsu, Shu-Ching, Chu, Yue-Ru, Lin, Mei-Yao, Jiaang, Weir-Tong, Chen, Ruey-Hwa, Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923824/
https://www.ncbi.nlm.nih.gov/pubmed/24551161
http://dx.doi.org/10.1371/journal.pone.0088772