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Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B

Despite the progress made in targeted anticancer therapies in recent years, challenges remain. The identification of new potential targets will ensure that the arsenal of cancer therapies continues to expand. FAM83B was recently discovered in a forward genetic screen for novel oncogenes that drive h...

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Detalles Bibliográficos
Autores principales: Cipriano, Rocky, Bryson, Benjamin L., Miskimen, Kristy L.S., Bartel, Courtney A., Hernandez-Sanchez, Wilnelly, Bruntz, Ronald C., Scott, Sarah A., Lindsley, Craig W., Brown, H. Alex, Jackson, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923847/
https://www.ncbi.nlm.nih.gov/pubmed/23912460
http://dx.doi.org/10.1038/onc.2013.293