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Ampelopsin Induces Cell Growth Inhibition and Apoptosis in Breast Cancer Cells through ROS Generation and Endoplasmic Reticulum Stress Pathway

Ampelopsin (AMP), a major bioactive constituent of Ampelopsis grossedentata, exerts a number of biological effects. In this study, we investigated its anti-cancer activity in human breast cancer cell lines, and explored the underlying mechanism of this action. Our results showed that treatment with...

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Detalles Bibliográficos
Autores principales: Zhou, Yong, Shu, Furong, Liang, Xinyu, Chang, Hui, Shi, Linying, Peng, Xiaoli, Zhu, Jundong, Mi, Mantian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923868/
https://www.ncbi.nlm.nih.gov/pubmed/24551210
http://dx.doi.org/10.1371/journal.pone.0089021