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Construction of synthetic nucleoli in human cells reveals how a major functional nuclear domain is formed and propagated through cell division

Human cell nuclei are functionally organized into structurally stable yet dynamic bodies whose cell cycle inheritance is poorly understood. Here, we investigate the biogenesis and propagation of nucleoli, sites of ribosome biogenesis and key regulators of cellular growth. Nucleolar and cell cycles a...

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Detalles Bibliográficos
Autores principales: Grob, Alice, Colleran, Christine, McStay, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923965/
https://www.ncbi.nlm.nih.gov/pubmed/24449107
http://dx.doi.org/10.1101/gad.234591.113