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Construction of synthetic nucleoli in human cells reveals how a major functional nuclear domain is formed and propagated through cell division
Human cell nuclei are functionally organized into structurally stable yet dynamic bodies whose cell cycle inheritance is poorly understood. Here, we investigate the biogenesis and propagation of nucleoli, sites of ribosome biogenesis and key regulators of cellular growth. Nucleolar and cell cycles a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923965/ https://www.ncbi.nlm.nih.gov/pubmed/24449107 http://dx.doi.org/10.1101/gad.234591.113 |