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lncRNA recruits RNAi and the exosome to dynamically regulate pho1 expression in response to phosphate levels in fission yeast

Numerous noncoding transcripts of unknown function have recently been identified. In this study, we report a novel mechanism that relies on transcription of noncoding RNA prt (pho1-repressing transcript) regulating expression of the pho1 gene. A product of this gene, Pho1, is a major secreted phosph...

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Detalles Bibliográficos
Autores principales: Shah, Sneha, Wittmann, Sina, Kilchert, Cornelia, Vasiljeva, Lidia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923966/
https://www.ncbi.nlm.nih.gov/pubmed/24493644
http://dx.doi.org/10.1101/gad.230177.113