Tempol Attenuates Renal Fibrosis in Mice with Unilateral Ureteral Obstruction: The Role of PI3K-Akt-FoxO3a Signaling

This study investigated whether tempol, an anti-oxidant, protects against renal injury by modulating phosphatidylinositol 3-kinase (PI3K)-Akt-Forkhead homeobox O (FoxO) signaling. Mice received unilateral ureteral obstruction (UUO) surgery with or without administration of tempol. We evaluated renal...

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Detalles Bibliográficos
Autores principales: Yoon, Hye Eun, Kim, Soo Jeong, Kim, Sung Jun, Chung, Sungjin, Shin, Seok Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924002/
https://www.ncbi.nlm.nih.gov/pubmed/24550650
http://dx.doi.org/10.3346/jkms.2014.29.2.230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924002/
https://www.ncbi.nlm.nih.gov/pubmed/24550650
http://dx.doi.org/10.3346/jkms.2014.29.2.230

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