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Kinotypes: stable species- and individual-specific profiles of cellular kinase activity

BACKGROUND: Recently, questions have been raised regarding the ability of animal models to recapitulate human disease at the molecular level. It has also been demonstrated that cellular kinases, individually or as a collective unit (the kinome), play critical roles in regulating complex biology. Des...

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Detalles Bibliográficos
Autores principales: Trost, Brett, Kindrachuk, Jason, Scruten, Erin, Griebel, Philip, Kusalik, Anthony, Napper, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924188/
https://www.ncbi.nlm.nih.gov/pubmed/24314169
http://dx.doi.org/10.1186/1471-2164-14-854