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Sample size calculation based on exact test for assessing differential expression analysis in RNA-seq data
BACKGROUND: Sample size calculation is an important issue in the experimental design of biomedical research. For RNA-seq experiments, the sample size calculation method based on the Poisson model has been proposed; however, when there are biological replicates, RNA-seq data could exhibit variation s...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924199/ https://www.ncbi.nlm.nih.gov/pubmed/24314022 http://dx.doi.org/10.1186/1471-2105-14-357 |