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Differential requirement for Dab2 in the development of embryonic and extra-embryonic tissues

BACKGROUND: Disabled-2 (Dab2) is an endocytic adaptor protein involved in clathrin-mediated endocytosis and cargo trafficking. Since its expression is lost in several cancer types, Dab2 has been suggested to be a tumor suppressor. In vitro studies indicate that Dab2 establishes epithelial cell polar...

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Detalles Bibliográficos
Autores principales: Moore, Robert, Cai, Kathy Qi, Tao, Wensi, Smith, Elizabeth R, Xu, Xiang-Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924344/
https://www.ncbi.nlm.nih.gov/pubmed/24168030
http://dx.doi.org/10.1186/1471-213X-13-39