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Imino sugar glucosidase inhibitors as broadly active anti-filovirus agents

Ebola virus and Marburg virus are members of the family of Filoviridae and are etiological agents of a deadly hemorrhagic fever disease. The clinical symptoms of Ebola and Marburg hemorrhagic fevers are difficult to distinguish and there are currently no specific antiviral therapies against either o...

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Detalles Bibliográficos
Autores principales: Chang, Jinhong, Guo, Ju-Tao, Du, Yanming, Block, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924557/
https://www.ncbi.nlm.nih.gov/pubmed/26038444
http://dx.doi.org/10.1038/emi.2013.77