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A microRNA network regulates proliferative timing and extracellular matrix synthesis during cellular quiescence in fibroblasts

BACKGROUND: Although quiescence (reversible cell cycle arrest) is a key part in the life history and fate of many mammalian cell types, the mechanisms of gene regulation in quiescent cells are poorly understood. We sought to clarify the role of microRNAs as regulators of the cellular functions of qu...

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Detalles Bibliográficos
Autores principales: Suh, Eric J, Remillard, Matthew Y, Legesse-Miller, Aster, Johnson, Elizabeth L, Lemons, Johanna MS, Chapman, Talia R, Forman, Joshua J, Kojima, Mina, Silberman, Eric S, Coller, Hilary A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924601/
https://www.ncbi.nlm.nih.gov/pubmed/23259597
http://dx.doi.org/10.1186/gb-2012-13-12-r121