RNAi-mediated silencing of MLL-AF9 reveals leukemia-associated downstream targets and processes

BACKGROUND: The translocation t(9;11)(p22;q23) leading to the leukemogenic fusion gene MLL-AF9 is a frequent translocation in infant acute myeloid leukemia (AML). This study aimed to identify genes and molecular processes downstream of MLL-AF9 (alias MLL-MLLT3) which could assist to develop new targ...

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Detalles Bibliográficos
Autores principales: Fleischmann, Katrin K, Pagel, Philipp, Schmid, Irene, Roscher, Adelbert A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924703/
https://www.ncbi.nlm.nih.gov/pubmed/24517546
http://dx.doi.org/10.1186/1476-4598-13-27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924703/
https://www.ncbi.nlm.nih.gov/pubmed/24517546
http://dx.doi.org/10.1186/1476-4598-13-27

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