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RNAi-mediated silencing of MLL-AF9 reveals leukemia-associated downstream targets and processes

BACKGROUND: The translocation t(9;11)(p22;q23) leading to the leukemogenic fusion gene MLL-AF9 is a frequent translocation in infant acute myeloid leukemia (AML). This study aimed to identify genes and molecular processes downstream of MLL-AF9 (alias MLL-MLLT3) which could assist to develop new targ...

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Detalles Bibliográficos
Autores principales:	Fleischmann, Katrin K, Pagel, Philipp, Schmid, Irene, Roscher, Adelbert A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924703/ https://www.ncbi.nlm.nih.gov/pubmed/24517546 http://dx.doi.org/10.1186/1476-4598-13-27

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