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Hes1 Oscillations Contribute to Heterogeneous Differentiation Responses in Embryonic Stem Cells

Embryonic stem (ES) cells can differentiate into multiple types of cells belonging to all three germ layers. Although ES cells are clonally established, they display heterogeneous responses upon the induction of differentiation, resulting in a mixture of various types of differentiated cells. Our re...

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Detalles Bibliográficos
Autores principales: Kobayashi, Taeko, Kageyama, Ryoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924840/
https://www.ncbi.nlm.nih.gov/pubmed/24710146
http://dx.doi.org/10.3390/genes2010219