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A quantitative model of amphetamine action on the 5-HT transporter

BACKGROUND AND PURPOSE: Amphetamines bind to the plasmalemmal transporters for the monoamines dopamine (DAT), noradrenaline (NET) and 5-HT (SERT); influx of amphetamine leads to efflux of substrates. Various models have been proposed to account for this amphetamine-induced reverse transport in mecha...

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Detalles Bibliográficos
Autores principales: Sandtner, Walter, Schmid, Diethart, Schicker, Klaus, Gerstbrein, Klaus, Koenig, Xaver, Mayer, Felix P, Boehm, Stefan, Freissmuth, Michael, Sitte, Harald H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & sons Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925039/
https://www.ncbi.nlm.nih.gov/pubmed/24251585
http://dx.doi.org/10.1111/bph.12520