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Vascular Endothelial Growth Factors Enhance the Permeability of the Mouse Blood-brain Barrier

The blood-brain barrier (BBB) impedes entry of many drugs into the brain, limiting clinical efficacy. A safe and efficient method for reversibly increasing BBB permeability would greatly facilitate central nervous system (CNS) drug delivery and expand the range of possible therapeutics to include wa...

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Detalles Bibliográficos
Autores principales: Jiang, Shize, Xia, Rui, Jiang, Yong, Wang, Lei, Gao, Fabao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925082/
https://www.ncbi.nlm.nih.gov/pubmed/24551038
http://dx.doi.org/10.1371/journal.pone.0086407