Preventing Disulfide Bond Formation Weakens Non-Covalent Forces among Lysozyme Aggregates

Nonnative disulfide bonds have been observed among protein aggregates in several diseases like amyotrophic lateral sclerosis, cataract and so on. The molecular mechanism by which formation of such bonds promotes protein aggregation is poorly understood. Here in this work we employ previously well ch...

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Detalles Bibliográficos
Autores principales: Ravi, Vijay Kumar, Goel, Mohit, Kotamarthi, Hema Chandra, Ainavarapu, Sri Rama Koti, Swaminathan, Rajaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925087/
https://www.ncbi.nlm.nih.gov/pubmed/24551048
http://dx.doi.org/10.1371/journal.pone.0087012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925087/
https://www.ncbi.nlm.nih.gov/pubmed/24551048
http://dx.doi.org/10.1371/journal.pone.0087012

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