Cargando…

Multiple Tumor Suppressor microRNAs Regulate Telomerase and TCF7, an Important Transcriptional Regulator of the Wnt Pathway

The human TERT (hTERT) gene encodes the telomerase catalytic subunit which plays a role in telomerase regulation. Telomerase is activated in more than 90% of all human malignancies and understanding how telomerase is regulated is necessary for implementation of successful anti-cancer therapies. micr...

Descripción completa

Detalles Bibliográficos
Autores principales: Hrdličková, Radmila, Nehyba, Jiří, Bargmann, William, Bose, Henry R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925088/
https://www.ncbi.nlm.nih.gov/pubmed/24551047
http://dx.doi.org/10.1371/journal.pone.0086990