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optGpSampler: An Improved Tool for Uniformly Sampling the Solution-Space of Genome-Scale Metabolic Networks

Constraint-based models of metabolic networks are typically underdetermined, because they contain more reactions than metabolites. Therefore the solutions to this system do not consist of unique flux rates for each reaction, but rather a space of possible flux rates. By uniformly sampling this space...

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Detalles Bibliográficos
Autores principales: Megchelenbrink, Wout, Huynen, Martijn, Marchiori, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925089/
https://www.ncbi.nlm.nih.gov/pubmed/24551039
http://dx.doi.org/10.1371/journal.pone.0086587