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optGpSampler: An Improved Tool for Uniformly Sampling the Solution-Space of Genome-Scale Metabolic Networks
Constraint-based models of metabolic networks are typically underdetermined, because they contain more reactions than metabolites. Therefore the solutions to this system do not consist of unique flux rates for each reaction, but rather a space of possible flux rates. By uniformly sampling this space...
Autores principales: | Megchelenbrink, Wout, Huynen, Martijn, Marchiori, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925089/ https://www.ncbi.nlm.nih.gov/pubmed/24551039 http://dx.doi.org/10.1371/journal.pone.0086587 |
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