TCRγδ(+)CD4(−)CD8(−) T Cells Suppress the CD8(+) T-Cell Response to Hepatitis B Virus Peptides, and Are Associated with Viral Control in Chronic Hepatitis B

The immune mechanisms underlying failure to achieve hepatitis B e antigen (HBeAg) seroconversion associated with viral control in chronic hepatitis B (CHB) remain unclear. Here we investigated the role of CD4(−)CD8(−) T (double-negative T; DNT) cells including TCRαβ(+) DNT (αβ DNT) and TCRγδ(+) DNT...

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Detalles Bibliográficos
Autores principales: Lai, Qintao, Ma, Shiwu, Ge, Jun, Huang, Zuxiong, Huang, Xuan, Jiang, Xiaotao, Li, Yongyin, Zhang, Mingxia, Zhang, Xiaoyong, Sun, Jian, Abbott, William G. H., Hou, Jinlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925121/
https://www.ncbi.nlm.nih.gov/pubmed/24551107
http://dx.doi.org/10.1371/journal.pone.0088475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925121/
https://www.ncbi.nlm.nih.gov/pubmed/24551107
http://dx.doi.org/10.1371/journal.pone.0088475

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