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TCRγδ(+)CD4(−)CD8(−) T Cells Suppress the CD8(+) T-Cell Response to Hepatitis B Virus Peptides, and Are Associated with Viral Control in Chronic Hepatitis B
The immune mechanisms underlying failure to achieve hepatitis B e antigen (HBeAg) seroconversion associated with viral control in chronic hepatitis B (CHB) remain unclear. Here we investigated the role of CD4(−)CD8(−) T (double-negative T; DNT) cells including TCRαβ(+) DNT (αβ DNT) and TCRγδ(+) DNT...
Autores principales: | Lai, Qintao, Ma, Shiwu, Ge, Jun, Huang, Zuxiong, Huang, Xuan, Jiang, Xiaotao, Li, Yongyin, Zhang, Mingxia, Zhang, Xiaoyong, Sun, Jian, Abbott, William G. H., Hou, Jinlin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925121/ https://www.ncbi.nlm.nih.gov/pubmed/24551107 http://dx.doi.org/10.1371/journal.pone.0088475 |
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