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β-catenin-mediated inhibition of cross-priming: A new mechanism for tumors to evade immunosurveillance
Cross-priming plays a major role in generating CD8(+) T cell-dependent antitumor immunity through cross-presentation. However, the cross-presentation of tumor-associated antigens by dendritic cells often promotes tolerance rather than CD8(+) T-cell immunity. We have now identified a β-catenin-depend...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925153/ https://www.ncbi.nlm.nih.gov/pubmed/24567866 http://dx.doi.org/10.4161/onci.26920 |