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Complement-Mediated Virus Infectivity Neutralisation by HLA Antibodies Is Associated with Sterilising Immunity to SIV Challenge in the Macaque Model for HIV/AIDS

Sterilising immunity is a desired outcome for vaccination against human immunodeficiency virus (HIV) and has been observed in the macaque model using inactivated simian immunodeficiency virus (SIV). This protection was attributed to antibodies specific for cell proteins including human leucocyte ant...

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Detalles Bibliográficos
Autores principales: Page, Mark, Quartey-Papafio, Ruby, Robinson, Mark, Hassall, Mark, Cranage, Martin, Stott, James, Almond, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925162/
https://www.ncbi.nlm.nih.gov/pubmed/24551145
http://dx.doi.org/10.1371/journal.pone.0088735