Systemic Delivery of siRNA Down Regulates Brain Prion Protein and Ameliorates Neuropathology in Prion Disorder

One of the main challenges for neurodegenerative disorders that are principally incurable is the development of new therapeutic strategies, which raises important medical, scientific and societal issues. Creutzfeldt-Jakob diseases are rare neurodegenerative fatal disorders which today remain incurab...

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Detalles Bibliográficos
Autores principales: Lehmann, Sylvain, Relano-Gines, Aroa, Resina, Sarah, Brillaud, Elsa, Casanova, Danielle, Vincent, Charles, Hamela, Claire, Poupeau, Sophie, Laffont, Mathieu, Gabelle, Audrey, Delaby, Constance, Belondrade, Maxime, Arnaud, Jacques-Damien, Alvarez, Maria-Teresa, Maurel, Jean-Claude, Maurel, Patrick, Crozet, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925167/
https://www.ncbi.nlm.nih.gov/pubmed/24551164
http://dx.doi.org/10.1371/journal.pone.0088797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925167/
https://www.ncbi.nlm.nih.gov/pubmed/24551164
http://dx.doi.org/10.1371/journal.pone.0088797

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