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Magnetic resonance imaging for monitoring therapeutic response in a transgenic mouse model of Alzheimer’s disease using voxel-based analysis of amyloid plaques

In this study, we have shown the potential of a voxel-based analysis for imaging amyloid plaques and its utility in monitoring therapeutic response in Alzheimer’s disease (AD) mice using manganese oxide nanoparticles conjugated with an antibody of Aβ1-40 peptide (HMON-abAβ40). T1-weighted MR brain i...

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Detalles Bibliográficos
Autores principales: Kim, Jae-Hun, Ha, Tae Lin, Im, Geun Ho, Yang, Jehoon, Seo, Sang Won, Chung, Julius Juhyun, Chae, Sun Young, Lee, In Su, Lee, Jung Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925172/
https://www.ncbi.nlm.nih.gov/pubmed/24518227
http://dx.doi.org/10.1097/WNR.0000000000000067