TrkB Agonist Antibody Pretreatment Enhances Neuronal Survival and Long-Term Sensory Motor Function Following Hypoxic Ischemic Injury in Neonatal Rats

Perinatal hypoxic ischemia (H-I) causes brain damage and long-term neurological impairments, leading to motor dysfunctions and cerebral palsy. Many studies have demonstrated that the TrkB-ERK1/2 signaling pathway plays a key role in mediating the protective effect of brain-derived neurotrophic facto...

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Detalles Bibliográficos
Autores principales: Kim, Gab Seok, Cho, Seongeun, Nelson, James W., Zipfel, Gregory J., Han, Byung Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925177/
https://www.ncbi.nlm.nih.gov/pubmed/24551199
http://dx.doi.org/10.1371/journal.pone.0088962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925177/
https://www.ncbi.nlm.nih.gov/pubmed/24551199
http://dx.doi.org/10.1371/journal.pone.0088962

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