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In-Depth Analysis Shows Synergy between Erlotinib and miR-34a

Tyrosine kinase inhibitors directed against epidermal growth factor receptor (EGFR-TKI), such as erlotinib, are effective in a limited fraction of non-small cell lung cancer (NSCLC). However, the majority of NSCLC and other cancer types remain resistant. Therapeutic miRNA mimics modeled after endoge...

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Detalles Bibliográficos
Autores principales: Zhao, Jane, Kelnar, Kevin, Bader, Andreas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925231/
https://www.ncbi.nlm.nih.gov/pubmed/24551227
http://dx.doi.org/10.1371/journal.pone.0089105