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LOXL2 catalytically inactive mutants mediate epithelial-to-mesenchymal transition

Lysyl-oxidase-like 2 (LOXL2) is a member of the lysyl oxidase family that catalyzes the cross-linking of collagens or elastins in the extracellular matrix, thus regulating the tensile strength of tissues. However, many reports have suggested different intracellular roles for LOXL2, including the abi...

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Detalles Bibliográficos
Autores principales: Cuevas, Eva P., Moreno-Bueno, Gema, Canesin, Giacomo, Santos, Vanesa, Portillo, Francisco, Cano, Amparo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925316/
https://www.ncbi.nlm.nih.gov/pubmed/24414204
http://dx.doi.org/10.1242/bio.20146841