Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth

Target of rapamycin complex 1 (TORC1), which controls growth in response to nutrients, promotes ageing in multiple organisms. The fission yeast Schizosaccharomyces pombe emerges as a valuable genetic model system to study TORC1 function and cellular ageing. Here we exploited the combinatorial action...

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Detalles Bibliográficos
Autores principales: Rallis, Charalampos, López-Maury, Luis, Georgescu, Teodora, Pancaldi, Vera, Bähler, Jürg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925319/
https://www.ncbi.nlm.nih.gov/pubmed/24463365
http://dx.doi.org/10.1242/bio.20147245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925319/
https://www.ncbi.nlm.nih.gov/pubmed/24463365
http://dx.doi.org/10.1242/bio.20147245

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