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The pivotal role of pyruvate dehydrogenase kinases in metabolic flexibility

Metabolic flexibility is the capacity of a system to adjust fuel (primarily glucose and fatty acids) oxidation based on nutrient availability. The ability to alter substrate oxidation in response to nutritional state depends on the genetically influenced balance between oxidation and storage capacit...

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Detalles Bibliográficos
Autores principales: Zhang, Shuai, Hulver, Matthew W, McMillan, Ryan P, Cline, Mark A, Gilbert, Elizabeth R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925357/
https://www.ncbi.nlm.nih.gov/pubmed/24520982
http://dx.doi.org/10.1186/1743-7075-11-10