Spectroscopic, Viscositic and Molecular Modeling Studies on the Interaction of 3′-Azido-Daunorubicin Thiosemicarbazone with DNA

A new daunorubicin has been synthesized and structurally characterized. The interaction of native calf thymus DNA (ctDNA) with 3′-azido-daunorubicin thiosemicarbazone (ADNRT) was investigated under simulated physiological conditions by multi-spectroscopic techniques, viscometric measurements and mol...

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Detalles Bibliográficos
Autores principales: Cui, Fengling, Liu, Qingfeng, Luo, Hongxia, Zhang, Guisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925501/
https://www.ncbi.nlm.nih.gov/pubmed/23974700
http://dx.doi.org/10.1007/s10895-013-1285-8