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CDK/CCN and CDKI Alterations for Cancer Prognosis and Therapeutic Predictivity

The regulation of cell growth and division occurs in an accurate sequential manner. It is dictated by the accumulation of cyclins (CCNs) and cyclin-dependent kinases (CDKs) complexes and degradation of CCNs. In human tumors, instead, the cell cycle is deregulated, causing absence of differentiation...

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Detalles Bibliográficos
Autores principales: Bonelli, Patrizia, Tuccillo, Franca Maria, Borrelli, Antonella, Schiattarella, Antonietta, Buonaguro, Franco Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925518/
https://www.ncbi.nlm.nih.gov/pubmed/24605326
http://dx.doi.org/10.1155/2014/361020