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rhPDGF-BB Promotes Proliferation and Osteogenic Differentiation of Bone Marrow Stromal Cells from Streptozotocin-Induced Diabetic Rats through ERK Pathway

Management of nonunion fracture and massive segmental bone defects in diabetes remains a challenging clinical problem. Bone marrow stromal cells (BMSCs) are crucial for bone remodeling and hold promise for bone regeneration. However, we have showed previously that diabetes can affect the proliferati...

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Detalles Bibliográficos
Autores principales: Zhao, Yanfang, Zhang, Songmei, Zeng, Deliang, Xia, Lunguo, Lamichhane, Ashwini, Jiang, Xinquan, Zhang, Fuqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925525/
https://www.ncbi.nlm.nih.gov/pubmed/24605332
http://dx.doi.org/10.1155/2014/637415