Hypoxia Enhances the Senescence Effect of Bortezomib—The Proteasome Inhibitor—On Human Skin Fibroblasts

The 26S proteasome inhibitor, bortezomib, selectively induces apoptosis in some cancer cells. However, the nature of its selectivity remains unknown. The study presented here provides novel information on cellular effects of bortezomib in normal fibroblasts. We have found that in normoxic conditions...

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Detalles Bibliográficos
Autores principales: Krętowski, Rafał, Borzym-Kluczyk, Małgorzata, Cechowska-Pasko, Marzanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925537/
https://www.ncbi.nlm.nih.gov/pubmed/24605321
http://dx.doi.org/10.1155/2014/196249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925537/
https://www.ncbi.nlm.nih.gov/pubmed/24605321
http://dx.doi.org/10.1155/2014/196249

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