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Functional Characterization of Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) N- and C-Terminal Domains during Xenopus laevis Development

Extracellular matrix (ECM) remodeling is essential for facilitating developmental processes. ECM remodeling, accomplished by matrix metalloproteinases (MMPs), is regulated by endogenous tissue inhibitors of metalloproteinases (TIMPs). While the TIMP N-terminal domain is involved in inhibition of MMP...

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Detalles Bibliográficos
Autores principales: Nieuwesteeg, M. A., Willson, J. A., Cepeda, M., Fox, M. A., Damjanovski, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925571/
https://www.ncbi.nlm.nih.gov/pubmed/24616631
http://dx.doi.org/10.1155/2014/467907