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Amelioration of Severe TNBS Induced Colitis by Novel AP-1 and NF-κB Inhibitors in Rats

AP-1 and NF-κB inhibitors, namely, DTCM-G and DHMEQ, were investigated in male Wistar rats with severe colitis, induced by TNBS. The animals were randomized into 3 groups. The control group received 0.5 mL of 0.5% of the vehicle i.p., the DTCM-G group received 22.5 mg/kg body weight DTCM-G in 0.5% i...

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Detalles Bibliográficos
Autores principales: El-Salhy, Magdy, Umezawa, Kazuo, Gilja, Odd Helge, Hatlebakk, Jan G., Gundersen, Doris, Hausken, Trygve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925602/
https://www.ncbi.nlm.nih.gov/pubmed/24616647
http://dx.doi.org/10.1155/2014/813804