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CDK6 binds and promotes the degradation of the EYA2 protein

Cyclin-dependent kinase 6 (Cdk6) is a D-Cyclin-activated kinase that is directly involved in driving the cell cycle through inactivation of pRB in G(1) phase. Increasingly, evidence suggests that CDK6, while directly driving the cell cycle, may only be essential for proliferation of specialized cell...

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Detalles Bibliográficos
Autores principales: Kohrt, Dawn, Crary, Jennifer, Zimmer, Marc, Patrick, Aaron N, Ford, Heide L, Hinds, Philip W, Grossel, Martha J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925736/
https://www.ncbi.nlm.nih.gov/pubmed/24196439
http://dx.doi.org/10.4161/cc.26755