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CtIP is required for DNA damage-dependent induction of P21

DNA endonuclease CtIP is involved in both DNA double-strand break (DSB) repair and transcriptional repression/activation. The cyclin-dependent kinase inhibitor P21, which is induced at transcription level in response to a variety of stresses, controls G(1)/S transition. In this report, we found that...

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Detalles Bibliográficos
Autores principales: Liu, Bo, Cong, Rixin, Peng, Bin, Zhu, Bingtao, Dou, Gelin, Ai, Haiyan, Zhang, Xiaodong, Wang, Zhenghe, Xu, Xingzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925741/
https://www.ncbi.nlm.nih.gov/pubmed/24196441
http://dx.doi.org/10.4161/cc.26810