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CGGBP1 phosphorylation constitutes a telomere-protection signal

The shelterin proteins are required for telomere integrity. Shelterin dysfunction can lead to initiation of unwarranted DNA damage and repair pathways at chromosomal termini. Interestingly, many shelterin accessory proteins are involved in DNA damage signaling and repair. We demonstrate here that in...

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Detalles Bibliográficos
Autores principales: Singh, Umashankar, Maturi, Varun, Jones, Rhiannon E, Paulsson, Ylva, Baird, Duncan M, Westermark, Bengt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925742/
https://www.ncbi.nlm.nih.gov/pubmed/24196442
http://dx.doi.org/10.4161/cc.26813