Single molecule FRET reveals pore size and opening mechanism of a mechano-sensitive ion channel

The mechanosensitive channel of large conductance, which serves as a model system for mechanosensitive channels, has previously been crystallized in the closed form, but not in the open form. Ensemble measurements and electrophysiological sieving experiments show that the open-diameter of the channe...

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Detalles Bibliográficos
Autores principales: Wang, Yong, Liu, Yanxin, DeBerg, Hannah A, Nomura, Takeshi, Hoffman, Melinda Tonks, Rohde, Paul R, Schulten, Klaus, Martinac, Boris, Selvin, Paul R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925968/
https://www.ncbi.nlm.nih.gov/pubmed/24550255
http://dx.doi.org/10.7554/eLife.01834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925968/
https://www.ncbi.nlm.nih.gov/pubmed/24550255
http://dx.doi.org/10.7554/eLife.01834

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