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Single molecule FRET reveals pore size and opening mechanism of a mechano-sensitive ion channel
The mechanosensitive channel of large conductance, which serves as a model system for mechanosensitive channels, has previously been crystallized in the closed form, but not in the open form. Ensemble measurements and electrophysiological sieving experiments show that the open-diameter of the channe...
Autores principales: | Wang, Yong, Liu, Yanxin, DeBerg, Hannah A, Nomura, Takeshi, Hoffman, Melinda Tonks, Rohde, Paul R, Schulten, Klaus, Martinac, Boris, Selvin, Paul R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925968/ https://www.ncbi.nlm.nih.gov/pubmed/24550255 http://dx.doi.org/10.7554/eLife.01834 |
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