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Genome sequencing and analysis of the paclitaxel-producing endophytic fungus Penicillium aurantiogriseum NRRL 62431

BACKGROUND: Paclitaxel (Taxol™) is an important anticancer drug with a unique mode of action. The biosynthesis of paclitaxel had been considered restricted to the Taxus species until it was discovered in Taxomyces andreanae, an endophytic fungus of T. brevifolia. Subsequently, paclitaxel was found i...

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Detalles Bibliográficos
Autores principales: Yang, Yanfang, Zhao, Hainan, Barrero, Roberto A, Zhang, Baohong, Sun, Guiling, Wilson, Iain W, Xie, Fuliang, Walker, Kevin D, Parks, Joshua W, Bruce, Robert, Guo, Guangwu, Chen, Li, Zhang, Yong, Huang, Xin, Tang, Qi, Liu, Hongwei, Bellgard, Matthew I, Qiu, Deyou, Lai, Jinsheng, Hoffman, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925984/
https://www.ncbi.nlm.nih.gov/pubmed/24460898
http://dx.doi.org/10.1186/1471-2164-15-69