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Detecting and correcting the bias of unmeasured factors using perturbation analysis: a data-mining approach

BACKGROUND: The randomized controlled study is the gold-standard research method in biomedicine. In contrast, the validity of a (nonrandomized) observational study is often questioned because of unknown/unmeasured factors, which may have confounding and/or effect-modifying potential. METHODS: In thi...

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Detalles Bibliográficos
Autor principal: Lee, Wen-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925987/
https://www.ncbi.nlm.nih.gov/pubmed/24499374
http://dx.doi.org/10.1186/1471-2288-14-18